How does an aldol condensation differ from an aldol addition?

• It adds a second enolate to the product
• It runs without any carbonyl partner
• It follows addition with dehydration to an enone

What is the product of an aldol addition?

• A beta-hydroxy carbonyl compound
• A beta-keto ester
• A conjugated diene with no oxygen

Ketones stop at the addition product because they have no group able to leave.

Circle one:   True   False

Why can mixing two different carbonyl partners give four products?

• Because each partner can play either role
• Because aldol products always split in two
• Because heating doubles every molecule

An ester enolate attacks another ester. What forms?

• A beta-hydroxy carbonyl that cannot change further
• A beta-keto ester after alkoxide leaves
• Two unchanged esters plus water

Which partner makes a clean acceptor for a crossed aldol?

• An aldehyde with no alpha hydrogens
• A ketone with two different alpha positions
• An ester enolate in large excess

A crossed aldol of two enolisable aldehydes gives a mess. What had to be controlled?

• The temperature of the room
• Which partner enolises and which accepts
• The colour of the reaction flask

An enone is cut beside its double bond for retrosynthesis. Where did each side come from?

• The carbonyl side was the donor and the alpha side the acceptor
• The carbonyl side was the acceptor and the alpha side the donor
• Both sides came from a single Claisen donor