On a COSY map you walk from proton A to B to C through cross-spots. What did you trace?

• The temperature of the room
• The price of the instrument
• A chain of coupled protons

What does each off-diagonal spot on a 2D map tell you?

• The sample has melted
• Two signals are connected
• One signal is an error

A one-bond map pairs each proton with the carbon holding it.

Circle one:   True   False

Two fragments sit on either side of a carbon with no protons. Which experiment joins them?

• Another COSY walk
• A long-range correlation map
• A weaker magnet

Your COSY walk gives a chain of four protons, and the one-bond map pairs each with a carbon. What do you hold now?

• A four-carbon fragment with its protons placed
• The full structure with every bond proven
• A single quaternary carbon

A structure rests on twenty COSY spots and one lone long-range spot. Which correlation carried the most weight?

• The lone long-range spot
• Both carry equal weight always
• The COSY chain with twenty supporting spots

A student assigns the whole structure from one long-range spot and ignores a COSY chain that contradicts it. What is the error?

• Using too many experiments
• Trusting the weakest link over stronger evidence
• Reading the carbon spectrum first

Two candidate structures both fit the COSY and one-bond data, differing only at one quaternary centre. What decides between them?

• The long-range spots across that centre
• Rerunning the proton spectrum louder
• Picking the prettier drawing