Vesicle Traffic: Coats, Adaptors and Fusion · seed 1 · A4, ink-friendly. The answer key prints on its own page for grown-ups.

Delivery vans of the cell

Science · Organisms & Life Processes · ages 18-20
Name ______________________   Date ____________
  1. Which route does COPII run?

    • Back to the ER
    • To the cell surface
    • From ER to Golgi
  2. The export line runs Golgi, then ER, then vesicle, then fusion. True or false?

    Circle one:   True   False

  3. COPI ferries strays back to the ER. True or false?

    Circle one:   True   False

  4. How does a vesicle fuse with its target?

    • SNAREs zipper the membranes
    • Cargo swims free across the gap
    • Coats dissolve the target
  5. What is the clathrin coat for?

    • Runs from the ER forward to the Golgi stack each cycle
    • Returns strays to the ER
    • Buds vesicles toward endosomes for sorting
  6. One coat type is blocked. What happens to the cargo that uses it?

    • That cargo piles up
    • Traffic speeds up
    • All coats take over perfectly
  7. A new protein must be secreted. What is its first station after the ribosome?

    • The Golgi
    • The cell membrane
    • The ER
  8. Faster budding is what stops a vesicle fusing with the wrong compartment. True or false?

    Circle one:   True   False

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Answer key

For grown-ups. Fold this page away before handing over the rest.

Delivery vans of the cell W1-mt_uq8R0bdB_L-s1

  1. From ER to Golgi · COPII carries fresh cargo forward to the Golgi.
  2. False · Building at the ER comes first and fusion comes last.
  3. True · COPI runs the return leg to the ER.
  4. SNAREs zipper the membranes · Zippering SNAREs pull the two membranes into one.
  5. Buds vesicles toward endosomes for sorting · Clathrin buds from the surface and the trans-Golgi toward endosomes.
  6. That cargo piles up · Each coat admits only matching cargo, so no substitute carries it.
  7. The ER · The ER builds secreted cargo before the Golgi ever sees it.
  8. False · Only matching labels pass the check, so speed cannot address cargo.
Worksheet · LightMySky