Delivery vans of the cell

Science · Organisms & Life Processes · ages 18-20

Name ______________________ Date ____________

Which route does COPII run?
- Back to the ER
- To the cell surface
- From ER to Golgi
Put the export line in order.
- Golgi, ER, vesicle, fusion
- ER, Golgi, vesicle, fusion
- Vesicle, ER, Golgi, fusion
Which route does COPI run?
- Back to the ER
- Forward to the Golgi
- Outside the cell
How does a vesicle fuse with its target?
- SNAREs zipper the membranes
- Cargo swims free across the gap
- Coats dissolve the target
What is the clathrin coat for?
- ER to Golgi runs
- Returning strays
- Buds for the membrane or outside, picking cargo with adaptors
One coat type is blocked. What happens to the cargo that uses it?
- That cargo piles up
- Traffic speeds up
- All coats take over perfectly
A new protein must be secreted. What is its first station after the ribosome?
- The Golgi
- The cell membrane
- The ER
What stops a vesicle from fusing with the wrong compartment?
- Faster budding
- Bigger vesicles
- Matching SNAREs and labels

Answer key

For grown-ups. Fold this page away before handing over the rest.

From ER to Golgi · COPII carries fresh cargo forward to the Golgi.
ER, Golgi, vesicle, fusion · Building precedes sorting, and delivery ends in fusion.
Back to the ER · COPI ferries strays back to the ER.
SNAREs zipper the membranes · Zippering SNAREs pull the two membranes into one.
Buds for the membrane or outside, picking cargo with adaptors · Clathrin handles the late legs toward the surface and beyond.
That cargo piles up · Each coat admits only matching cargo, so no substitute carries it.
The ER · The ER builds secreted cargo before the Golgi ever sees it.
Matching SNAREs and labels · Only matching labels pass the check, so wrong addresses refuse fusion.