What should a 22-year-old be learning?
At age 22, 115 topics open up across Science, Mathematics, Computing. Each one has prerequisites that come first, so the order matters more than the list: Hamilton's Principle and the Action is a typical starting point.
How do I know what a 22-year-old already knows?
LightMySky starts by assuming everything below the learner’s level is already known, then checks the assumption as they practise. What holds up stays lit; what does not comes back for review.
Science
- Hamilton's Principle and the ActionForces & Motion · on the way
- The Hamiltonian, Phase Space and the Canonical EquationsForces & Motion · on the way
- The Grand Canonical Ensemble and the Chemical PotentialThermal & Statistical Physics · on the way
- Reading a Paper and Its Supporting InformationChemistry · on the way
- Searching the Chemical Literature by Structure and by ReactionChemistry · on the way
- Characterisation Standards: What Counts as Proof of a New CompoundChemistry · on the way
- Solid-State Synthesis: Controlling Phase, Defect and DopantChemistry · on the way
- Porous Frameworks: Zeolites, Metal-Organic Frameworks and What They HoldChemistry · on the way
- Chain Growth and Step Growth: Two Routes to a PolymerChemistry · on the way
- Strategy in Retrosynthesis: Strategic Bonds and Convergent RoutesChemistry · on the way
- Protecting Group Strategy: Orthogonality and the Order of RemovalChemistry · on the way
- Structure Elucidation from a Complete Data SetChemistry · on the way
- Nuclear Magnetic Resonance Past Assignment: Relaxation, the Nuclear Overhauser Effect and ExchangeChemistry · on the way
- Reducible Representations and Predicting Infrared and Raman ActivityChemistry · on the way
- Choosing Between Vibrational Methods: Infrared, Raman and Resonance RamanChemistry · on the way
- Single-Crystal Diffraction: From Reflections to a Refined StructureChemistry · on the way
- Substrate Control of Stereochemistry: Models for Facial SelectivityChemistry · on the way
- Asymmetric Catalysis: Where Enantioselectivity Comes FromChemistry · on the way
- Organocatalysis: Enamine and Iminium ActivationChemistry · on the way
- Cross-Coupling in Practice: Choosing Ligand, Base and ConditionsChemistry · on the way
- States as Vectors: Dirac Notation and the State SpaceQuantum & Modern Physics · on the way
- Observables as Hermitian Operators and Their SpectraQuantum & Modern Physics · on the way
- Commutators, Compatible Observables and the General Uncertainty RelationQuantum & Modern Physics · on the way
- Poisson Brackets and Constants of the MotionForces & Motion · on the way
- Noether's Theorem: Symmetry and Conserved QuantitiesForces & Motion · on the way
- From Coordinates to Fields: the Lagrangian DensityForces & Motion · on the way
- Unitary Time Evolution and the Heisenberg PictureQuantum & Modern Physics · on the way
- Angular Momentum from Its Commutation RelationsQuantum & Modern Physics · on the way
- Covariant Electrodynamics and the Field TensorElectricity & Magnetism · on the way
- Gauge Freedom and the Potentials as the Working VariablesElectricity & Magnetism · on the way
- Ideal Quantum Gases and Bose-Einstein CondensationThermal & Statistical Physics · on the way
- Fluctuations, Linear Response and the Fluctuation-Dissipation RelationThermal & Statistical Physics · on the way
- Phase Transitions, Order Parameters and Broken SymmetryThermal & Statistical Physics · on the way
- Dimensional Analysis, Scaling and the Order-of-Magnitude EstimateScientific Inquiry · on the way
- Fitting a Model to Data: Least Squares, Chi-Square and Goodness of FitScientific Inquiry · on the way
- Systematic Error, Controls and the Design of a MeasurementScientific Inquiry · on the way
- Cancer as Clonal Evolution: Drivers, Passengers and Selection in a TissueGenetics & Evolution · on the way
- What a Cell Has to Break to Become a TumourOrganisms & Life Processes · on the way
- Oncogenes and Tumour Suppressors: Why One Allele Is Sometimes EnoughGenetics & Evolution · on the way
- Alignment Scoring: Substitution Matrices, Gap Penalties and SignificanceGenetics & Evolution · on the way
- Hidden Markov Models for Sequence: Profiles, States and DecodingGenetics & Evolution · on the way
- Models of Sequence Evolution and Maximum Likelihood TreesGenetics & Evolution · on the way
- Bayesian Phylogenetics: Priors, Sampling and Judging ConvergenceGenetics & Evolution · on the way
- Phylogenomics: Gene Trees, Species Trees and Why They DisagreeGenetics & Evolution · on the way
- Differential Expression from Counts: Dispersion, Fit and ShrinkageGenetics & Evolution · on the way
- Designing a Biological Experiment: Units, Controls and RandomisationScientific Inquiry · on the way
- Pseudoreplication: When n Is Smaller Than It LooksScientific Inquiry · on the way
- Power and Effect Size, Decided Before the DataScientific Inquiry · on the way
- Researcher Degrees of Freedom and the Pre-registered Analysis PlanScientific Inquiry · on the way
- Reading a Primary Paper: The Claim, the Figure and the Missing ControlScientific Inquiry · on the way
- Gene Regulatory Networks: Motifs and What They ComputeGenetics & Evolution · on the way
- Stochastic Gene Expression: Bursting, Noise and Cell-to-Cell VariationGenetics & Evolution · on the way
- Single-Cell RNA Sequencing: From Droplets to a Count MatrixGenetics & Evolution · on the way
- Mapping Regulatory Elements: Accessibility, Occupancy and ContactGenetics & Evolution · on the way
- Genome Engineering: Cut Site, Repair Choice and Editing OutcomeGenetics & Evolution · on the way
- Base and Prime Editing: Changing a Letter Without Breaking Both StrandsGenetics & Evolution · on the way
- The Tumour Microenvironment: Stroma, Hypoxia and Immune ExclusionOrganisms & Life Processes · on the way
- Targeted Therapy and the Resistance That Follows ItOrganisms & Life Processes · on the way
- Checkpoint Blockade: Taking a Brake Off a T CellThe Human Body · on the way
Mathematics
- Reading a Mathematics PaperMathematical Thinking · on the way
- Writing a Proof Someone Else Can CheckMathematical Thinking · on the way
- Sigma-Algebras and Measurable SetsCalculus & Analysis · on the way
- Outer Measure and the Construction of Lebesgue MeasureCalculus & Analysis · on the way
- Measurable Functions and Approximation by Simple FunctionsCalculus & Analysis · on the way
- The Lebesgue Integral and What It RepairsCalculus & Analysis · on the way
- Monotone Convergence, Fatou and Dominated ConvergenceCalculus & Analysis · on the way
- Product Measure and Fubini's TheoremCalculus & Analysis · on the way
- Lp Spaces and the Inequalities They Rest OnCalculus & Analysis · on the way
- Normed Spaces, Completeness and Banach SpacesCalculus & Analysis · on the way
- The Fourier Transform on the LineCalculus & Analysis · on the way
- Classifying Second-Order PDEs and What the Type DecidesDifferential Equations · on the way
- Separation of Variables and the Heat EquationDifferential Equations · on the way
- The Wave Equation and Its CharacteristicsDifferential Equations · on the way
- Laplace's Equation and the Maximum PrincipleDifferential Equations · on the way
- Weak Solutions and Test FunctionsDifferential Equations · on the way
- Conditional Expectation Given a Sigma-AlgebraProbability · on the way
- Markov Chains and the Memoryless AssumptionProbability · on the way
- Stationary Distributions and Long-Run BehaviourProbability · on the way
- Normal Subgroups and Quotient GroupsAbstract Algebra · on the way
- Group Actions, Orbits and the Class EquationAbstract Algebra · on the way
- The Sylow Theorems and Groups of Small OrderAbstract Algebra · on the way
- Ideals and Quotient RingsAbstract Algebra · on the way
- Polynomial Rings, Irreducibility and Unique FactorisationAbstract Algebra · on the way
- Modules: Linear Algebra Over a RingAbstract Algebra · on the way
- Field Extensions and Their DegreesAbstract Algebra · on the way
- Group Representations and the Group AlgebraAbstract Algebra · on the way
- Maschke's Theorem and Complete ReducibilityAbstract Algebra · on the way
- The Galois CorrespondenceAbstract Algebra · on the way
- Definitions as Design DecisionsMathematical Thinking · on the way
- Counterexamples and Testing a ConjectureMathematical Thinking · on the way
Computing
- Randomised Algorithms and the Probabilistic MethodAlgorithms & Data Structures · on the way
- Concentration Bounds and a High-Probability GuaranteeAlgorithms & Data Structures · on the way
- Approximation Ratios and How One Is ProvedAlgorithms & Data Structures · on the way
- Linear Programming, Duality and RoundingAlgorithms & Data Structures · on the way
- Complexity Beyond NP: Space, Randomness and the HierarchyAlgorithms & Data Structures · on the way
- SAT Solvers and What Makes Search PracticalAlgorithms & Data Structures · on the way
- Attention as a Learned LookupMachine Learning · on the way
- The Transformer Block: Heads, Residuals and NormalisationMachine Learning · on the way
- Tokenisation and What a Model Actually ReadsMachine Learning · on the way
- Pretraining by Predicting the Next TokenMachine Learning · on the way
- Scaling Laws and the Compute BudgetMachine Learning · on the way
- Adapting a Pretrained Model: Fine-Tuning and Low-Rank UpdatesMachine Learning · on the way
- Generative Models: Learning a Distribution You Can SampleMachine Learning · on the way
- Diffusion Models: Learning to Undo NoiseMachine Learning · on the way
- Markov Decision Processes: States, Actions and ReturnMachine Learning · on the way
- Impossibility Under Asynchrony: What Consensus Cannot PromiseNetworks & Security · on the way
- Raft: Leader Election and Log ReplicationNetworks & Security · on the way
- Quorums, Leases and Changing the MembershipNetworks & Security · on the way
- Linearizability and Checking a HistoryNetworks & Security · on the way
- Distributed Transactions and the Blocking Case of Two-Phase CommitData & Databases · on the way
- Conflict-Free Replicated Data TypesData & Databases · on the way
- Log-Structured Storage and CompactionData & Databases · on the way
- Reading a Systems or Machine-Learning PaperSoftware Engineering · on the way
- Benchmarks and the Traps in ThemMachine Learning · on the way
- Specifying Correctness: Safety, Liveness and InvariantsSoftware Engineering · on the way